Emerging Treatments for Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) affects an estimated 1% of the US population, and approximately 50% of cases are considered severe. Individuals with OCD have been reported to have significant functional disability and worse quality of life compared with those without the condition. First-line treatments — cognitive behavioral therapy (CBT) that includes exposure and response prevention, and…

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A New Angle On Anxiety

Clinical anxiety affects up to 30 percent of Americans who are in great need of better treatments with fewer side effects. A study from Boston Children’s Hospital, published September 6 by the journal Molecular Psychiatry, finds that certain neurons in the hypothalamus play a central, previously unknown role in triggering anxiety. Targeting them, rather than…

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Cognitive Impairment, Depression in the Workplace

In a society that depends on intellectual productivity for competitiveness in our economy, impairment in work function can be detrimental. In order to maximize “human capital,” there is mounting interest in understanding how to optimize brain health at both the individual and population level. It is well established that mental illness significantly affects individuals’ ability…

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Adult ADHD: Recognition and Treatment Approaches

Attention-deficit/hyperactivity disorder is commonly perceived as a condition that is manifested, diagnosed, and treated in childhood. However, an estimated 5% of adults worldwide have the disorder, and long-term follow-up studies suggest that it persists into adulthood in half of those diagnosed in childhood. The number of diagnoses of attention-deficit/hyperactivity disorder (ADHD) is climbing overall, in…

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Depression’s Physical Source Discovered

Understanding of the physical root of depression has been advanced, thanks to new research. Researchers have identified the lateral orbitofrontal cortex as the area of the brain affected by depression. This discovery could open up possible new treatments, say the researchers. The study shows that depression affects the part of the brain which is implicated…

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Stimulating Neural Circuits With Magnetism

Brain stimulation might sound like some Frankensteinian demonstration from a Victorian science fair. But in reality, it is a contemporary technique making a huge impact in neuroscience by addressing a longstanding limitation of traditional methods for investigating human brain function. Such techniques, like EEG and fMRI, can only be used to infer the effects of…

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Depression May Accelerate Brain Aging

Individuals diagnosed with major depressive disorder (MDD) present with accelerated aging of certain brain structures such as the putamen. Published in Journal of Psychiatry & Neuroscience, the study was led and co-authored by Dr Sacchet at the Department of Psychology, Stanford University. The putamen, together with the caudate nucleus and globus pallidus, represents a part…

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Groundbreaking Study Roots Out Signs of Depression in Brain

According to a new study, depression is tied to increased functional connectivity between a brain region that is associated with not receiving rewards and experiencing punishing events (the lateral orbitofrontal cortex) and an area of the brain involved in someone’s sense of self (the precuneus). This cutting-edge discovery was published today in the journal Brain….

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Associations Between Comorbid Cigarette, Alcohol, and Marijuana Use and Psychopathology

Researchers from New York University and the University of Pittsburgh have found that in a large, community-based sample, long-term simultaneous use of alcohol, cigarettes, and marijuana was associated with psychiatric disorders in adulthood, including Antisocial Personality Disorder (ASPD), Major Depressive Episode (MDE), and Generalized Anxiety Disorder (GAD). The findings were published in the Journal of…

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Low Levels of Vitamin D in Patients With Bipolar Disorder

Over the years, researchers have pointed to a potential link between vitamin D deficiency and neuropsychiatric illness, including major depressive disorder and schizophrenia. A new report provides further evidence that confirms the association between low vitamin D and bipolar disorder. A group of Dutch researchers published their findings in the Journal of Clinical Psychopharmacology. It…

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