Peripheral Inflammatory Markers Are Associated With Psychomotor Retardation in Major Depressive Disorder

Plasma inflammatory markers are associated with psychomotor retardation in individuals diagnosed with major depressive disorder, according to a report published in Brain, Behavior, and Immunity, the official journal of Psychoneuroimmunology Research Society.

Major depressive disorder (MDD) has the highest lifetime prevalence of any neuropsychiatric disorder and is a leading cause of disability worldwide.2 Currently available antidepressant medications fail to treat a significant number of patients.

It is known that psychomotor retardation – one of the criterions for the diagnosis of MDD – is associated with poor response to antidepressant treatment.4,5 In the current study, Dr Goldsmith and colleagues investigated whether immune system activation is associated with psychomotor speed in untreated individuals diagnosed with MDD.

Read the full article at http://www.psychiatryadvisor.com/mood-disorders/inflammation-and-psychomotor-speed-in-mdd/article/504749/